Clozapine is a medication used in the treatment of schizophrenia. It is an atypical antipsychotic and is regulated by the Therapeutic Goods Administration (TGA) and subsidised under the Highly Specialised Drugs Program.

Clozapine, trade name Clozaril® or Clopine®, may cause serious side effects in a very small proportion of the population especially if stopped abruptly or recommenced at the regular dose after a period of non-compliance, for instance in the event of a patient being admitted to hospital and not being able to tell staff that they are taking clozapine.

SA Mental Health Services are committed to providing clinicians and consumers with state wide standardised resources that will assist in the safe and effective management of consumers who are taking clozapine.

For more information

For information regarding clozapine management please contact the local clozapine coordinator at your nearest Community Mental Health Centre.


Important information

Shared care pathways


Alert instructions and screen captures

Flow charts

Forms and protocols


Questionnaires and assessments

GP information

Clozapine shared care checklist: (see Appendix 4 of Clozapine Management Clinical Guideline (PDF 2.4MB)

The resources listed below are information for people who have been prescribed clozapine and their carers. 

Resources for clinicians