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Potential Clozapine Drug Interactions - important information about drug interactions for the Clozapine Group
For example constipation, urinary retention, delirium
Starting or stopping smoking can cause dramatic changes in clozapine blood levels
Prescription medications used for smoking cessation have been associated with destabilisation of mental state in some patients. Consider a strategic approach in consultation with a psychiatrist. Clozapine levels must be monitored in people ceasing smoking to avoid clozapine toxicity. Refer to the Clozapine Management Clinical Guideline (CMCG) (PDF 3.95MB) for required monitoring.