COVID-19: Treatment recommendations for hospitalised adult patients Clinical Guideline

Version 5.1 approved 29 April 2024

Since the emergence of COVID-19 there have been significant developments in the antiviral and immunomodulatory medications recommended for patients hospitalised with COVID-19.

The COVID-19: Treatment Recommendations for Hospitalised Adult Patients Clinical Guideline (PDF 916KB) only addresses the use of disease-modifying treatments for COVID-19 in hospitalised adult patients.

This guideline does not:

provide guidance of the overall care for patients with COVID-19
provide advice regarding supportive therapies recommended for COVID-19
provide information regarding the prevention or chemoprophylaxis for the prevention of COVID-19.

For information related to the management and care of patients with COVID-19 please refer to:

COVID–19 (SARS–COV–2) – Management Guide (CALHN–PRC05409) — on eCentral
CALHN COVID–19 internet page

Medication recommendations for COVID-19 can change rapidly due to medication shortages, ongoing research and as novel agents are discovered. For the most up to date Australian guidelines and recommendations refer to:

Topics covered in this guideline

Definition of COVID-19 disease severity for adults
Risk factors for progressing to severe or critical illness
Classification of immunosuppressed patients including medications associated with a reduced immune response to COVID-19 vaccination
COVID-19 treatment recommendations for hospitalised adults according to disease severity (excluding pregnancy/breastfeeding) – mild illness
COVID-19 treatment recommendations for hospitalised adults according to disease severity (excluding pregnancy/breastfeeding) – moderate to critical illness
Assessing a patient for nirmatrelvir plus ritonavir (Paxlovid®)
COVID-19 treatment recommendations for hospitalised pregnant and breastfeeding adults
Approach to treatment of immunocompromised patients with persistent or relapsed COVID-19 infection
Access and restrictions to therapy
Treatments for COVID-19 - Drug Monographs

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Last updated: 31 Jul 2024

COVID-19: Treatment recommendations for hospitalised adult patients Clinical Guideline

Topics covered in this guideline

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