Clozapine is a medication used in the treatment of schizophrenia. It is an atypical antipsychotic and is regulated by the Therapeutic Goods Administration (TGA) and subsidised under the Highly Specialised Drugs Program.
Clozapine, tradename Clozaril® or Clopine®, may cause serious side effects in a very small proportion of the population especially if stopped abruptly or recommenced at the regular dose after a period of non-compliance, for instance in the event of a patient being admitted to hospital and not being able to tell staff that they are taking clozapine.
SA Mental Health Services are committed to providing clinicians and consumers with state wide standardised resources that will assist in the safe and effective management of consumers who are taking clozapine.
For more information
For information regarding clozapine management please contact the local clozapine coordinator at your nearest Community Mental Health Centre.
Resources for clinicians
Potential Clozapine drug interactions: See page 34 of Clinical Guideline (PDF 2.4MB)
Shared care pathways: See Appendix 2 of Clinical Guideline (PDF 2.4MB)
Alert instructions and screen captures
Forms and protocols
Clozapine prescription example: (see Appendix 5 of Clozapine Management Clinical Guideline (PDF 2.4MB))
Questionnaires and assessments
Clozapine shared care checklist: (see Appendix 4 of Clozapine Management Clinical Guideline (PDF 2.4MB))
Resources for consumers
The resources listed below are information for people who have been prescribed clozapine and their carers.