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South Australian Neonatal Medication Guidelines 

Nutrient delivery 
comparison tables: 

Preterm Infants 
 Comparison of breast milk, preterm formula and term formula,+/- 

fortification and/or vitamin supplementation at feed volumes of 
160mL/kg/day  

  Department for Health and Wellbeing, Government of South Australia. All rights reserved.  

INFORMAL COPY WHEN PRINTED  Page 1 of 8 

Public-I4-A1 
 
 

Note:
This guideline provides advice of a general nature.  This statewide guideline has been prepared to promote and facilitate 
standardisation and consistency of practice, using a multidisciplinary approach.  The guideline is based on a review of 
published evidence and expert opinion.  
Information in this statewide guideline is current at the time of publication.  
SA Health does not accept responsibility for the quality or accuracy of material on websites linked from this site and does not 
sponsor, approve or endorse materials on such links. 
Health practitioners in the South Australian public health sector are expected to review specific details of each patient and 
professionally assess the applicability of the relevant guideline to that clinical situation. 
If for good clinical reasons, a decision is made to depart from the guideline, the responsible clinician must document in the 
patient s medical record, the decision made, by whom, and detailed reasons for the departure from the guideline. 
This statewide guideline does not address all the elements of clinical practice and assumes that the individual clinicians are 
responsible for discussing care with consumers in an environment that is culturally appropriate and which enables respectful 
confidential discussion. This includes: 

  The use of interpreter services where necessary, 
  Advising consumers of their choice and ensuring informed consent is obtained, 
  Providing care within scope of practice, meeting all legislative requirements and maintaining standards of 

professional conduct, and  
  Documenting all care in accordance with mandatory and local requirements 

Practice Points 

The following tables list recommended nutritional intakes (RNIs)                                                  
for preterm infants up to 2500grams 

&gt; Composition of fortifiers and formulas vary, and should be taken into account when 
prescribing additional supplementation. The following tables may be used as an adjunct to 
dose calculations for nutritional supplements such as vitamin D, iron and folic acid in 
preterm infants. 

&gt; Nutrient content comparisons are made against published Recommended Nutrient Intakes 
(RNIs) for very low birth weight preterm infants. 

&gt; Koletzko (2014) RNIs listed in these tables are based on evidence for preterm infants with 
weights less than and equal to 1500grams. Alternative recommendations include 
ESPGHAN (2010), which list RNIs for those infants less than and equal to 1800grams. 
These values can be generally used for preterm infants up to 2500g as there are no other 
published RNIs for this age group (consensus recommendation with South Australian 
neonatal units). 

&gt; For babies greater than 2500grams, the National Health and Medical Research Council 
Nutrient Reference Values for infants 0-6 months can be used. 

&gt; Efforts have been taken to ensure the accuracy of the tables but changes to fortifier and 
formula composition made by manufacturers may result in small variations. 



South Australian Neonatal Medication Guidelines - Nutrient delivery comparison tables: Preterm Infants  

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&gt; These tables provide information to compare nutrients delivered by 
&gt; breastmilk fortified with commercial fortifiers and preterm formulas with 

referenced preterm infant recommended nutrient intakes when fed at 
160mL/kg/day and when fed at 160mL/kg/day with the addition of daily 
Penta-vite Infant 0.45mL 

&gt; unfortified breastmilk with selected standard strength term formulas with 
referenced preterm infant recommended nutrient intakes when fed at 
160mL/kg/day and when fed at 160mL/kg/day with the addition of daily 
Penta-vite Infant 0.45mL, Colecalciferol 10microg, Vitamin E 10.5mg (0.1mL) 
and Folic acid 62.5microg 

&gt; unfortified breastmilk with standard strength and fortified elemental formulas 
when fed at 160mL/kg/day with the addition of daily Penta-vite Infant 0.45mL, 
Colecalciferol 10microg, Vitamin E 10.5mg (0.1mL) and Folic acid 62.5microg  

&gt; Penta-vite  Infant contains B group vitamins and ascorbic acid (vitamin C), which are not 
listed in the general table s RNIs (with the exception of folic acid). 

 

Comparison of nutrients delivered by breastmilk fortified with commercial fortifiers and preterm 
formulas at feed volumes of 160mL/Kg/day 

Comparison of nutrients delivered by breastmilk fortified with commercial fortifiers and preterm 
formulas at feed volumes of 160mL/Kg/day, with the addition of daily Penta-vite Infant 0.45mL  

Comparison of nutrients delivered by unfortified breastmilk and selected standard strength term 
formulas given at 160ml/kg/day 

Comparison of nutrients delivered by unfortified breastmilk and selected standard strength term 
formulas given at 160ml/kg/day, with the addition of daily Penta-vite Infant 0.45mL, Colecalciferol 
(D3) 10microg, Vitamin E 10.5mg (0.1ml), and Folic acid 62.5microg 

Comparison of nutrients delivered by unfortified breastmilk and selected standard strength and 
fortified elemental formulas given at 160ml/kg/day, with the addition of daily Penta-vite Infant 
0.45mL, Colecalciferol (D3) 10microg, Vitamin E 10.5mg (0.1ml), and Folic acid 62.5microg 
 

 

 
 
 



 South Australian Neonatal Medication Guidelines - Nutrient delivery comparison tables: Preterm Infants 

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Comparison of nutrients delivered by breastmilk fortified with commercial fortifiers and preterm formulas at feed volumes of 160mL/Kg/day 
Units are /kg/day with the exception of Vitamin D RNI which is a daily intake regardless of weight. Blue and red highlights indicate intakes &lt;75% and &gt;125% respectively of the lower and upper limits of the 
Koletzko recommended intakes for preterm infants 2014. This table is an extract from the Flinders Medical Centre Enteral Feeding Guideline.  
 

 Notes: Mature Breastmilk average composition   NHMRC, 2012 Infant feeding guidelines; NHMRC, Nutrient Reference Values ANZ, 2005.*DHA highly variable in line with maternal diet. Preterm Breastmilk week 2-8 macronutrient 
content used for calculations. Micronutrient content of mature EBM used. 

 

Koletzko et al 2014 Preterm Infant 
Recommended Nutrient Intakes 
/kg/day  
  Except Vit D which is daily 

intake  

Mature 
Breastmilk 
 
NHMRC 
 

Preterm 
Breastmilk 
Week2-8 
Boyce et al 
2016 

Preterm 
Breastmilk 
Week 1 
Boyce et al 
2016 

S26  Alula LBW  
(Aspen) 

EBM + S26 
Alula HMF 
(Aspen) 
4 sachets/100ml 

Aptamil Gold+ 
Preterm 
(Nutricia) 

EBM + Nutricia 
Breast Milk 
Fortifier 
2 sachets/100mL 

PreNAN Gold 
(Nestle) 

EBM + PreNAN 
HMF 
(Nestle) 
4 sachets/100ml 

Energy (cals) 110-135 112 105 91 128 128 130 131 128 133 

Protein (g) 3.5-4.5 1.7 2.0 3.0 4.3 3.6 4.2 4.0 4.6 4.3 

Type of Protein  60% Whey 40% Casein   
60% Whey 

40% Casein  
60% Whey 

40% Casein 

50% /50% 
extensively 

hydrolysed Whey 
/ Casein 

100% partially 
hydrolysed whey 

100% partially 
hydrolysed whey 

Fat (g) 4.8-6.6 7.0 5.5 4.1 6.1 5.7 6.2 5.6 6.4 6.7 

Type of Fat         39% MCT Fortifier 61% MCT 

DHA (mg) 18-60 17.9   27.2 2.9 21.8 17.9 23.1 26.9 

Carbohydrate (g) 11.6-13.2 11.0 11.7 10.5 14.0 15.3 13.4 16.2 13.0 13.8 

Type of carbohydrate  Lactose 100%   Lactose 50% 
Fortifier 15% 
lactose 85% 

maltodextrin.  
Lactose 56% 

Fortifier 
Maltodextrin 

100% 
Lactose 45% 

Fortifier 
Maltodextrin 

100% 
Sodium (mg) 69-115 27.2   86.4 56.0 112 84.80 80.96 86.08 

Calcium (mg) 120-200 51.2   161.6 198.4 150.4 156.8 185.6 172.8 

Phosphorus (mg) 60-140 19.8   83.2 92.8 99.2 80.6 123.2 90.2 

Iron (mg) 2 - 3 0.04   2.8 0.04 2.6 0.04 2.9 2.9 

Zinc (mg) 1.4-2.5 0.4   1.9 0.8 1.8 1.4 1.9 1.9 

Vitamin A (microg) 400-1100 49.6   576.0 484.8 577.6 420.8 592.0 580.8 

Vitamin D (microg) 10-25 0.2   5.4 12.3 4.8 8.2 5.9 5.8 

Vitamin E (mg) 2.2-11 0.8   5.3 5.6 5.6 4.9 5.8 6.8 

Vitamin K (microg) 4.4-28.0 0.4   10.1 18.3 9.6 10.64 10.24 12.4 

Folic acid  (microg) 35-100 13.6   56.0 61.6 56.0 61.6 65.6 73.8 

Osmolality mOsm/kg 
water  ~275   298    293 390 



South Australian Neonatal Medication Guidelines - Nutrient delivery comparison tables: Preterm Infants  

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Comparison of nutrients delivered by breastmilk fortified with commercial fortifiers and preterm formulas at feed volumes of 160mL/Kg/day, 
with the addition of daily Penta-vite Infant 0.45mL fixed dose/day*  
*contribution from Penta-vite Infant identified in brackets and is fixed dose/day regardless of weight. Adequacy to meet RNI needs individual calculation for affected nutrients. 
Units are /kg/day with the exceptions of Vitamin D RNI value &amp; supplementation value which are daily intake regardless of weight. Blue and red highlights indicate intakes &lt;75% and &gt;125% respectively of the 
lower and upper limits of the Koletzko recommended intakes for preterm infants 2014. This table is an extract from the Flinders Medical Centre Enteral Feeding Guideline. 

 Notes: Mature Breastmilk average composition   NHMRC, 2012 Infant feeding guidelines; NHMRC, Nutrient Reference Values ANZ, 2005.*DHA highly variable in line with maternal diet. Preterm Breastmilk week 2-8 macronutrient 
content used for calculations. Micronutrient content of mature EBM used.   

Koletzko et al 2014 Preterm Infant 
Recommended Nutrient Intakes 
/kg/day  
  Except Vit D which is daily intake  

Mature 
Breastmilk 
 
NHMRC 

Preterm 
Breastmilk 
Week2-8 
Boyce et al 2016 

Preterm 
Breastmilk 
Week 1 
Boyce et al 2016 

S26 Alula LBW  
(Aspen) 

EBM + S26 Alula 
HMF 
(Aspen) 
4 sachets/100ml 

Aptamil Gold+ 
Preterm 
(Nutricia) 

EBM + Nutricia 
Breast Milk 
Fortifier 
2 sachets/100ml 

PreNAN Gold 
(Nestle) 

EBM + PreNAN 
HMF 
(Nestle) 
4 sachets/100ml 

Energy (cals) 110-135 112 105 91 128 128 130 131 128 133 

Protein (g) 3.5-4.5 1.7 2.0 3.0 4.3 3.6 4.2 4.0 4.6 4.3 
Type of Protein 

 60% Whey 40% Casein   
60% Whey 

40% Casein  
60% Whey 

40% Casein 

50% /50% 
extensively 

hydrolysed Whey 
/ Casein 

100% partially 
hydrolysed whey 

100% partially 
hydrolysed whey 

Fat (g) 4.8-6.6 7.0 5.5 4.1 6.1 5.7 6.2 5.5 6.4 6.7 
Type of Fat         39% MCT Fortifier 61% MCT 

DHA (mg) 18-60 17.9   27.2 2.9 21.8 17.9 23.1 26.9 

Carbohydrate (g) 11.6-13.2 11.0 11.7 10.5 14.0 15.3 13.4 16.2 13.0 13.8 
Type of 
carbohydrate  Lactose 100%   Lactose 50% 

Fortifier 15% 
lactose 85% 

maltodextrin.  
Lactose 56% 

Fortifier 
Maltodextrin 

100% 
Lactose 45% 

Fortifier 
Maltodextrin 

100% 
Sodium (mg) 69-115 27.2   86.4 56.0 112.0 84.8 81.0 86.1 
Calcium (mg) 120-200 28.4   161.6 198.4 150.4 156.8 185.6 172.8 
Phosphorus (mg) 60-140 19.8   83.2 92.8 99.2 80.6 123.2 90.2 

Iron (mg) 2 - 3 0.04   2.8 0.04 2.6 0.04 2.9 2.9 
Zinc (mg) 1.4-2.5 0.4   1.9 0.8 1.8 1.4 1.9 1.9 

Vitamin A (microg) 400-1100 49.6 (+490)   576.0 (+490) 484.8 (+490) 577.6 (+490) 420.8 (+490) 592.0 (+490) 580.8 (+490) 
Vitamin D (microg) 10-25 0.2 (+10)   5.4 (+10) 12.3 (+10) 4.8 (+10) 8.2 (+10) 5.9 (+10) 5.8 (+10) 
Vitamin E (mg) 2.2-11 0.8   5.3 5.6 5.6 4.9 5.8 6.8 

Vitamin K (microg) 4.4-28.0 0.4   10.1 18.3 9.6 10.6 10.2 12.4 
Folic acid  (microg) 35-100 13.6   56.0 61.6 56.0 61.6 65.6 73.8 

Osmolality 
mOsm/kg water  ~275   298    293 390 



South Australian Neonatal Medication Guidelines - Nutrient delivery comparison tables: Preterm Infants  

INFORMAL COPY WHEN PRINTED                  Page 5 of 8 
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Comparison of nutrients delivered by unfortified breastmilk and selected standard strength term formulas given at 160ml/kg/day 
Units are /kg/day with the exception of Vitamin D RNI value which is a daily intake regardless of weight. Blue and red highlights indicate intakes &lt;75% and &gt;125% respectively of the lower and upper limits of the 

Koletzko recommended intakes for preterm infants 2014. This table is an extract from the Flinders Medical Centre Enteral Feeding Guideline. 

 Notes: Mature Breastmilk average composition   NHMRC, 2012 Infant feeding guidelines; NHMRC, Nutrient Reference Values ANZ, 2005. *DHA highly variable in line with maternal diet. Analyses based on powdered formulas made up as 
per directions 

Koletzko et al 2014 Preterm Infant 
Recommended Nutrient Intakes 
/kg/day  
  Except Vit D which is daily 

intake 

Mature 
Breastmilk 
 
NHMRC 

NAN 
Supreme 1 
(Nestle) 

Alfare 
(Nestle) 

Monogen 
(Nutricia) 
 

S26 Alula 
Lactose Free 
1 
(Aspen) 

Neocate Gold 
(Nutricia) 

Aptamil 
Gold + 
Pepti-Junior 
(Nutricia) 

Aptamil 
Profutura 
(Nutricia)  

NAN  
OptiPro Gold 
1 
(Nestle) 

S26 Alula 
Gold 
Newborn 
(Aspen) 

Energy (cals) 110-135 112 107 107 120 107 107 106 102 107 106 

Protein (g) 3.5-4.5 1.6 2.1 3.2 3.5 2.4 3.0 2.9 2.2 2.1 2.1 

Type of Protein  60% Whey 40% Casein 

100% partially 
hydrolysed 

whey 

100% 
extensively 
hydrolysed 

whey 

100% Whole 
whey 

60% Whey 
40% Casein Amino Acids 

100% 
extensively 
hydrolysed 

whey 

60% Whey 
40% Casein 

70% Whey 
30% Casein 

65% Whey 
35% Casein 

Fat (g) 4.8-6.6 7.0 5.6 5.4 3.5 5.8 5.4 5.6 5.6 5.8 5.8 

Type of Fat   MCT 0% MCT 40% MCT 84% MCT 0% MCT 31% MCT 51% MCT 0% MCT 0% MCT 0% 

DHA (mg) 18-60 17.92 13.0 9.1 0.0 0.0 18.1 10.7 22.4 12.6 19.2 

Carbohydrate (g) 11.6-13.2 11.02 12.2 11.7 18.6 11.5 11.5 10.9 10.9 11.8 11.5 

Type of 
carbohydrate  Lactose 100% 

Lactose 58% 
Maltodextrin 

Lactose 
&lt;0.01g/100ml Lactose 0% Lactose 0% Lactose 0% 

Lactulose 
&lt;0.1g/100mL Lactose 100% 

Lactose  
Maltodextrin Lactose 100% 

Sodium (mg) 69-115 27.2 44.8 52.8 56.0 28.8 41.8 28.8 33.6 27.2 28.8 

Calcium (mg) 120-200 51.2 80.0 81.6 96.0 88.0 123.8 80.0 76.8 68.8 72.0 

Phosphorus (mg) 60-140 19.8 44.8 54.4 56.0 59.2 87.7 44.8 48.0 38.4 41.6 

Iron (mg) 2 - 3 0.04 1.1 1.1 1.8 1.3 1.6 1.2 1.2 1.1 1.3 

Zinc (mg) 1.4-2.5 0.4 1.1 1.1 1.0 1.0 1.2 0.8 0.8 1.1 1.0 

Vitamin A (microg) 400-1100 49.6 110.4 112.0 87.4 110.4 89.6 83.2 96.0 108.8 96.0 

Vitamin D (microg) 10-25 0.2 1.4 1.6 3.2 1.9 1.9 2.1 1.2 1.4 1.9 

Vitamin E (mg) 2.2-11 0.8 2.1 1.8 1.3 1.2 1.0 1.6 2.2 1.8 1.2 

Vitamin K (microg) 4.4-28.0 0.4 9.4 8.6 4.8 10.7 9.4 7.5 8.8 9.0 10.7 

Folate (microg) 35-100 13.6 17.6 13.0 18.2 17.6 14.1 14.2 18.2 16 17.6 

Osmolality 
mOsm/kg water  295 322 217 

235 
  340 210  311  



South Australian Neonatal Medication Guidelines - Nutrient delivery comparison tables: Preterm Infants  

INFORMAL COPY WHEN PRINTED                  Page 6 of 8 
Public-I4-A1 

 

Comparison of nutrients delivered by unfortified breastmilk and selected standard strength term formulas given at 160ml/kg/day, with the 
addition of daily Penta-vite Infant 0.45mL, Colecalciferol (D3) 10microg, Vitamin E 10.5mg (0.1ml), and Folic acid 62.5microg 
*contribution from nutrient supplements identified in brackets and is fixed dose/day regardless of weight. Adequacy to meet RNI needs individual calculation for affected nutrients. 
Units are /kg/day with the exceptions of Vitamin D RNI value &amp; supplement value which is a daily intake regardless of weight. Blue and red highlights indicate intakes &lt;75% and &gt;125% respectively of the lower 
and upper limits of the Koletzko recommended intakes for preterm infants 2014. This table is an extract from the Flinders Medical Centre Enteral Feeding Guideline. 

 Notes: Mature Breastmilk average composition   NHMRC, 2012 Infant feeding guidelines; NHMRC, Nutrient Reference Values ANZ, 2005. *DHA highly variable in line with maternal diet. Analyses based on powdered formulas made up as 
per directions 

 

Koletzko et al 2014 Preterm Infant 
Recommended Nutrient Intakes 
/kg/day  
  Except Vit D which is daily 

intake  

Mature 
Breastmilk 
 
NHMRC 

NAN 
Supreme 1 
(Nestle) 

Alfare 
(Nestle) 

Monogen 
(Nutricia) 
 

S26 Alula 
Lactose Free 
1 
(Aspen) 

Neocate Gold 
(Nutricia) 

Aptamil Gold 
+ Pepti-Junior 
(Nutricia) 

Aptamil 
Profutura 1 
(Nutricia)  

NAN  
OptiPro Gold 
1 
(Nestle) 

S26 Alula 
Gold 
Newborn 
(Aspen) 

Energy (cals) 110-135 112 107 107 120 107 107 106 102 107 106 

Protein (g) 3.5-4.5 1.6 2.1 3.2 3.5 2.4 3.0 2.9 2.2 2.1 2.1 

Type of Protein  60% Whey 40% Casein 

100% partially 
hydrolysed 

whey 

100% 
extensively 
hydrolysed 

whey 

100% Whole 
whey 

60% Whey 
40% Casein Amino Acids 

100% 
extensively 
hydrolysed 

whey 

60% Whey 
40% Casein 

70% Whey 
30% Casein 

65% Whey 
35% Casein 

Fat (g) 4.8-6.6 7.01 5.6 5.4 3.5 5.8 5.4 5.6 5.6 5.8 5.8 

Type of Fat   MCT 0% MCT 40% MCT 84% MCT 0% MCT 31% MCT 51% MCT 0% MCT 0% MCT 0% 

DHA (mg) 18-60 17.9 13.0 9.1 0.0 0.0 18.1 10.7 22.4 12.6 19.2 

Carbohydrate (g) 11.6-13.2 11.0 12.2 11.7 18.6 11.5 11.5 10.9 10.9 11.8 11.5 
Type of 
carbohydrate  Lactose 100% 

Lactose 58% 
Maltodextrin 

Lactose 
&lt;0.01g/100ml Lactose 0% Lactose 0% Lactose 0% 

Lactose 
&lt;0.1g/100mL Lactose 100% 

Lactose  
Maltodextrin Lactose 100% 

Sodium (mg) 69-115 27.2 44.8 52.8 56.0 28.8 41.8 28.8 33.6 27.2 28.8 

Calcium (mg) 120-200 51.2 80.0 81.6 96.0 88.0 123.8 80.0 76.8 68.8 72.0 

Phosphorus (mg) 60-140 19.8 44.8 54.4 56.0 59.2 87.7 44.8 48.0 38.4 41.6 

Iron (mg) 2 - 3 0.04 1.1 1.1 1.8 1.3 1.6 1.2 1.2 1.1 1.3 

Zinc (mg) 1.4-2.5 0.4 1.1 1.1 1.0 1.0 1.2 0.8 0.8 1.1 1.0 

Vitamin A (microg) 400-1100 49.6 (+490) 107.2 (+490) 112.0 (+490) 87.4 (+490) 110.4 (+490) 89.6 (+490) 83.2 (+490) 96.0 (+490) 108.8 (+490) 96.0 (+490) 

Vitamin D (microg) 10-25 0.2 (+20) 1.4 (+20) 1.6 (+20) 3.2 (+20) 1.9 (+20) 1.9 (+20) 2.1 (+20) 1.2 (+20) 1.4 (+20) 1.9 (+20) 

Vitamin E (mg) 2.2-11 0.8 (+10.5) 2.1 (+10.5) 1.8 (+10.5) 1.3 (+10.5) 1.2 (+10.5) 1.0 (+10.5) 1.6 (+10.5) 2.2 (+10.5) 1.8 (+10.5) 1.2 (+10.5) 

Vitamin K (microg) 4.4-28.0 0.4 9.4 8.6 4.8 10.7 9.4 7.5 8.8 9.0 10.7 

Folate (microg) 35-100 13.6 (+62.5) 17.6 (+62.5) 13.0 (+62.5) 18.2 (+62.5) 17.2 (+62.5) 23.5 (+62.5) 14.2 (+62.5) 18.2 (+62.5) 16 (+62.5) 17.6 (+62.5) 
Osmolality 
mOsm/kg water  295 322 217 235  340 210  311  



South Australian Neonatal Medication Guidelines - Nutrient delivery comparison tables: Preterm Infants  

INFORMAL COPY WHEN PRINTED                  Page 7 of 8 
Public-I4-A1 

 

Comparison of nutrients delivered by unfortified breastmilk and selected standard strength and fortified elemental formulas given at 
160ml/kg/day, with the addition of daily Penta-vite Infant 0.45mL, Colecalciferol (D3) 10microg, Vitamin E 10.5mg (0.1ml), and Folic acid 
62.5microg 
*contribution from nutrient supplements identified in brackets and is fixed dose/day regardless of weight. Adequacy to meet RNI needs individual calculation for affected nutrients. 
Units are /kg/day with the exceptions of Vitamin D RNI value &amp; supplement which is a daily intake regardless of weight. Blue and red highlights indicate intakes &lt;75% and &gt;125% respectively of the lower and 
upper limits of the Koletzko recommended intakes for preterm infants 2014. This table is an extract from the Flinders Medical Centre Enteral Feeding Guideline. 

Notes: Mature Breastmilk average composition   NHMRC, 2012 Infant feeding guidelines; NHMRC, Nutrient Reference Values ANZ, 2005. *DHA highly variable in line with maternal diet. Analyses based on powdered formulas made up as 
per directions 

Koletzko et al 2014 Preterm Infant 
Recommended Nutrient Intakes 
/kg/day  
  Except Vit D which is daily intake 

Mature Breastmilk 
 
NHMRC 

Neocate Gold  
(Nutricia) 

Neocate Gold 
125% Strength 
(Nutricia) 

Elecare  
LCP 
(Abbott) 

Elecare 
LCP 
125% Strength 
(Abbott) 

Alfamino 
(Nestle) 

Alfamino 
125% Strength 
(Nestle) 

Energy (cals) 110-135 112 107 134.1 108.8 136.0 112.0 140.0 

Protein (g) &lt;1kg  4-4.5 
1-1.8kg 3.5 -4.0 1.6 3.0 3.8 3.5 4.5 3.0 3.8 

Type of Protein  60% Whey 40% Casein Amino Acids Amino Acids Amino Acids Amino Acids Amino Acids Amino Acids 

Fat (g) 4.8-6.6 7.0 5.4 6.9 5.4 6.9 5.4 6.9 

Type of Fat &lt;40% MCT  MCT 31% MCT 31% MCT 33% MCT 33% MCT 25% MCT 25% 

DHA (mg) 18-60 17.9 18.1 22.6 9.9 12.5 11.2 14.1 

Carbohydrate (g) 11.6-13.2 11.0 11.5 14.4 12.5 15.7 12.6 15.8 

Type of carbohydrate  Lactose 100% Lactose 0% Lactose 0% Lactose 0% Lactose 0% Lactose 0% Lactose 0% 

Sodium (mg) 69-115 27.2 41.8 52.2 54.4 68.0 40.0 50.1 

Calcium (mg) 120-200 51.2 123.8 154.9 129.6 162.1 91.2 114.1 

Phosphorus (mg) 60-140 19.8 87.7 109.6 98.1 122.6 62.4 78.1 

Iron (mg) 2 - 3 0.04 1.6 2.1 1.9 2.4 1.1 1.4 

Zinc (mg) 1.4-2.5 0.4 1.2 1.5 1.3 1.6 1.1 1.4 

Vitamin A (microg) 400-1100 49.6 (+490) 89.6 (+490) 112.0 (+490) 118.4 (+490) 148 (+490) 129.6 (+490) 162.1 (+490) 

Vitamin D (microg) 10-25 0.2 (+20) 1.9 (+20) 2.4 (+20) 1.6 (+20) 2.1 (+20) 1.4 (+20) 1.8 (+20) 

Vitamin E (mg) 2.2-11 0.8 (+10.5) 1.0 (+10.5) 1.3 (+10.5) 2.1 (+10.5) 2.6 (+10.5) 2.7 (+10.5) 3.4 (+10.5) 

Vitamin K (microg) 4.4-28.0 0.4 9.4 11.8 12.8 16.0 9.8 12.2 

Folate (microg) 35-100 13.6 (+62.5) 23.5 (+62.5) 29.4 (+62.5) 39.4 (+62.5) 49.3 (+62.5) 13.4 (+62.5) 16.8 (+62.5) 

Osmolality mOsm/kg 
water  295 340      



 South Australian Neonatal Medication Guidelines - Nutrient delivery comparison tables: Preterm Infants 

INFORMAL COPY WHEN PRINTED Page 8 of 8 

Public-I4-A1 

References 
? Flinders Medical Centre Enteral Feeding Guidelines 

? Agostoni C, Buonocore V, Caniellie, M et al.  Enteral Nutrient Supply for Preterm Infants: 
Commentary From the European Society for Paediatric Gastroenterology, Hepatology, and 
Nutrition Committee on Nutrition  J Paediatr Gastroenerol Nutr 2010;50:85-91 

? Koletzko B, Poindexter B &amp; Uauy R  Recommended Nutrient Intake Levels for Stable, fully 
Enterally Fed Very Low Birth Weight Infants  in Koletzko B, Poindexter B, Uauy R (eds): 
Nutritional Care of Preterm Infants: Scientific Basis and Practical Guidelines. World Rev 
Nutr Diet. Basel, Karger, 2014, vol 110, pp 297-299 

Document Ownership &amp; History 
Developed by: 
Contact: 
Endorsed by:  
Next review due: 
ISBN number:  
PDS reference:  
Policy history: 

SA Maternal, Neonatal &amp; Gynaecology Community of Practice 
Health.NeoMed@sa.gov.au 
SA Health Safety and Quality Strategic Governance Committee 
12/02/2024 
978-1-76083-057-1
CG306
Is this a new policy (V1)?  Y
Does this policy amend or update and existing policy?   N
If so, which version?
Does this policy replace another policy with a different title?  N 
If so, which policy (title)?

Approval 
Date Version 

Who approved New/Revised 
Version Reason for Change 

12/02/2019 V1 
SA Health Safety and Quality 
Strategic Governance 
Committee 

Original SA Health Safety and Quality 
Strategic Governance Committee 
approved version 



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