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Measles - including symptoms, treatment and prevention

Measles is an illness caused by infection with the measles virus.

Measles is a notifiable condition1

How measles is spread

Measles is spread when an infected person talks, breathes, coughs or sneezes tiny particles containing infectious agents into the air. These are called small particle aerosols. Due to their tiny size, small particle aerosols can travel long distances on air currents and remain suspended in the air for minutes to hours. These small particle aerosols may be breathed in by another person. Measles is also spread by contact with hands, tissues and other articles soiled by nose and throat discharges. The virus is very infectious and droplets in the air may infect people entering a room up to 30 minutes after an infected person has left it.

Until the late 1960s almost everyone caught measles during childhood in Australia. As a result almost all people born in Australia before 1966 are immune to measles.

The gradual introduction of measles vaccine since then has resulted in the average age of cases in Australia increasing. Most cases now occur in people aged older than 20 years.

Outbreaks in recent years have followed the introduction of the virus from outside Australia.

Signs and symptoms

an adult with the measles rash all over their backEarly in the infection, symptoms may include:

  • fever
  • tiredness
  • cough
  • sore throat
  • runny nose
  • sore eyes
  • photophobia (discomfort when looking at light).

Image courtesy Prof. David Gordon, Flinders Medical Centre, Adelaide, South Australia.

These symptoms usually worsen over 3 to 5 days, then a blotchy rash (see image) begins on the head and over the next day or two spreads down the entire body.

The rash lasts 4 to 7 days. Measles illness usually lasts about 10 days. The cough may be the last symptom to disappear.

Measles is often a severe disease, frequently followed by middle ear infection (7% of cases) or bacterial pneumonia (lung infection or inflammation) in 6% of cases. In as many as 1 in every 1000 cases, brain infection occurs (encephalitis), often resulting in death or permanent brain damage. Sometimes brain damage may not appear until many years later.

a child with the measles rash all over their faceComplications from measles are more common and more severe in the chronically ill and in very young children.

Image Courtesy, Public Health Image Library (PHIL), Department of Health and Human Services, Centers for Disease Control and Prevention (CDC-USA)

Diagnosis

The diagnosis is suspected from the clinical presentation and can be confirmed by a blood test, or detection of the virus in urine, throat or eye specimens.

Incubation period

(time between becoming infected and developing symptoms)

Usually 10 days to onset of fever (range 7 to 18 days) and about 14 days to onset of rash.

Infectious period

(time during which an infected person can infect others)

From 24 hours before the onset of symptoms to four days after the appearance of the rash.

Treatment

There is no specific antiviral treatment for measles. Complications may require antibiotic treatment. Treatment for the symptoms includes plenty of fluids and paracetamol for the fever. Aspirin should not be given to children under 12 years of age unless specifically recommended by a doctor.

Prevention

Exclude the person with measles from childcare, preschool, school and work for at least 4 days after the onset of the rash.

Exclusion periods for contacts*:

  • In most circumstances, contacts who are not immune to measles should be excluded from childcare, preschool, school and work for 18 days after the last contact with an infectious person.
  • Where the contact with an infectious person occurs in an early childhood education and care services or primary school setting, or if the contact is immune-suppressed, advice on the exclusion period should be sought from the Communicable Disease Control Branch of SA Health (1300 232 272).

*A contact is any person who has been close enough to an infected person to be at risk of having acquired the infection from that person. 

Immunisation and immunoglobulin

Measles is best prevented by the measles, mumps and rubella (MMR) combination vaccine or the measles, mumps, rubella and varicella (MMRV) combination vaccine

Almost all people who have 2 doses of a measles-containing vaccine will be protected against measles.

If an unimmunised child aged 9 months of age or older or adult has contact with measles, the infection may be prevented by immediate vaccination (within 72 hours of first contact with an infectious person) with a measles-containing vaccine (unless contraindicated). If it is more than 3 days (73 hours) and within 6 days (144 hours) since the first exposure, immunoglobulin (a solution containing human antibodies that is made from human blood products) may prevent infection.

If the infant is less than 9 months old and is in contact with measles, the risk of developing measles can be reduced by giving immunoglobulin within 6 days (144 hours) of first contact.. The MMR vaccine should then be given as close as possible to 12 months of age, but at least 5 to 6 months after giving immunoglobulin. The measles-mumps-rubella-varicella (MMRV) vaccine due at 18 months of age should still be given at that time.

Adults born during or since 1966 are very likely to be susceptible to measles. Unless they have had a medically confirmed infection with measles they should ensure that they have had 2 documented doses of a measles containing vaccine. This is especially important prior to travel out of Australia.

Useful links


1 – In South Australia the law requires doctors and laboratories to report some infections or diseases to SA Health. These infections or diseases are commonly referred to as 'notifiable conditions'.

Image - Face of boy with measles; third day of rash. Image Courtesy of Public Health Image Library (PHIL), Department of Health and Human Services, Centers for Disease Control and Prevention (CDC-USA)

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